From the American Academy of Orthopedic Surgeons Patient Safety Committee The AAOS Patient Safety Committee recommends avoiding musculoskeletal corticosteroid injections for two weeks before and one week after COVID vaccine administration. Musculoskeletal corticosteroid injections are common procedures which are most often performed in an elective, outpatient setting. These can include intra-articular, bursal, tendon, and neuraxial injections. Currently there is no direct evidence of the impact of corticosteroid injections on vaccine efficacy. Corticosteroid injections have been shown to cause hypothalamic-pituitary-adrenal suppression. Increased risk of influenza infection has been associated with corticosteroids. It is unknown if corticosteroid injections could result in decreased immunogenicity which could reduce vaccine efficacy. The majority of musculoskeletal cortisone injections are elective procedures that can be safely postponed or rescheduled. Given the potential ...